1-2 Cups of Coffee a Day... Increases Survival Rate
However, No Effect on 'Liver Disease' Mortality
"Recommended Daily Coffee Intake for Adults: Up to Four Cups"
A study has found that consuming 1 to 2 cups of coffee per day positively affects survival rates, but it does not significantly impact the mortality rate of patients with liver disease. Pixabay
A study has found that consuming one to two cups of coffee per day positively affects survival rates, while it does not significantly impact mortality rates in patients with liver disease.
On the 26th, a team led by Professor Ryu Dam from the Department of Gastroenterology at Soonchunhyang University Seoul Hospital (including Professors Jang Jaeyoung, Jung Seungwon, Jang Young, and Clinical Lecturer Yang Kyungmo from the Department of Gastroenterology at Seoul St. Mary's Hospital) evaluated the effects of coffee consumption on metabolic dysfunction-associated fatty liver disease and metabolic alcoholic fatty liver disease using data from the UK Biobank.
Previous studies have repeatedly suggested that coffee may inhibit the progression of liver disease. In 2021, a joint research team from the University of Southampton and the University of Edinburgh in the UK analyzed the relationship between coffee drinking habits and the incidence of liver disease in approximately 500,000 people using UK Biobank data. They reported that coffee consumption reduced the incidence of chronic liver disease, fatty liver, liver cancer, and mortality due to liver disease. The research team explained that coffee drinkers had a 21% lower risk of developing chronic liver disease compared to non-drinkers and also showed a reduced risk of hepatocellular carcinoma, the most common form of liver cancer.
In this study, to more accurately analyze the impact of coffee consumption on survival rates in liver disease, inverse probability weighting was applied to adjust for other confounding variables. The researchers divided a total of 455,870 participants into groups without fatty liver, with metabolic dysfunction-associated fatty liver disease, and with metabolic alcoholic fatty liver disease. These groups were further categorized based on daily coffee consumption into 0 cups, 1?2 cups, and 3 or more cups, and a large-scale cohort analysis was conducted. Before applying inverse probability weighting, it was confirmed that consuming one to two cups of coffee per day increased survival rates in all groups: those without fatty liver, those with metabolic dysfunction-associated fatty liver disease, and those with metabolic alcoholic fatty liver disease.
However, after applying inverse probability weighting, coffee consumption did not affect liver disease-related mortality in either the metabolic dysfunction-associated fatty liver disease group or the metabolic alcoholic fatty liver disease group. Professor Ryu Dam stated, “Coffee consumption positively influences overall survival rates but does not significantly impact liver disease-related mortality. This is a more accurate analysis result obtained by additionally using the tool of confounding variable adjustment in previous studies.”
Coffee is known to be rich in various antioxidant and anticancer components such as chlorogenic acid and caffeine, which reduce the risk of Alzheimer's disease, Parkinson's disease, obesity, and heart failure. Numerous studies have also shown that coffee significantly lowers the incidence and mortality of heart disease. However, caffeine in coffee can negatively interact with medications taken to treat health problems. Additionally, in cases of diabetes, it may raise blood sugar levels and complicate insulin management. The recommended daily coffee intake for the general adult population is four cups or less (caffeine 400 mg).
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