"Currently in Clinical Trials...
Consult a Doctor Before Taking"
A study has found that the antipyretic analgesic aspirin may have the effect of inhibiting cancer metastasis. Whether this can be applied to actual humans requires further clinical trials to confirm, but the research team expects it to be a great help in developing effective anti-metastatic therapies to prevent cancer metastasis.
According to the UK BBC recently, Professor Rahul Roychoudhury's team at the University of Cambridge in the UK announced on the 6th in the scientific journal Nature that they discovered a new immune suppression pathway through experiments on cancer model mice, where aspirin prevented cancer from metastasizing to other organs in mice.
The research team found that aspirin inhibits cyclooxygenase 1, an inflammation-related enzyme in platelets, reducing the production of thromboxane (TXA2) in platelets, which weakens immune T cell suppression and thereby enhances the ability to fight metastatic cancer cells.
When aspirin was administered to various cancer model mice, including breast cancer, melanoma, and colon cancer, the rate of cancer cells metastasizing to other organs such as the lungs and liver was lower compared to the control group that did not receive aspirin.
The research team stated, "This suggests that aspirin can be an inexpensive and effective adjuvant therapy that enhances the natural immune response in mice to prevent cancer metastasis," and added, "Combining aspirin with other immunotherapies in the future could further strengthen the anti-metastatic effect."
However, the research team warned, "Aspirin can cause serious side effects in some people, and clinical trials on the safe and effective use of aspirin for preventing cancer metastasis are ongoing," advising, "Consult a doctor before starting aspirin intake."
Professor Ruth Langley of University College London (UCL) called it an "important discovery," saying, "Clinical trials will help identify who can benefit the most from aspirin."
She added, "Aspirin can cause serious side effects such as bleeding or gastric ulcers in some people," emphasizing, "It is important to determine which cancer patients may benefit from aspirin and always consult a doctor before taking it."
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