Green Tea Extract 'Polyphenol'... Using Carbon Quantum Dots
Research on Commercialization of Atopy Treatment by Companies Also Conducted
Dong-A University (President Lee Hae-woo) announced on the 7th that the research team led by Professors Kim Su-hwan and Koo Min-soo from the Department of Chemical Engineering published a paper in the SCI-level international journal ‘ACS Applied Materials & Interfaces’ and was selected for the Supplementary Cover.
‘ACS Applied Materials & Interfaces’ is an international journal published by the world-renowned chemical publisher, the American Chemical Society, with an impact factor of 9.5, reflecting its prestige.
The paper, led by first author Master’s student Han Jeong-min, is titled ‘Superoxide Dismutase-mimetic Polyphenol-based Carbon Dots for Multimodal Bioimaging and Treatment of Atopic Dermatitis.’
This research was supported by the ‘Basic Research Program’ of the Ministry of Science and ICT and the National Research Foundation of Korea, as well as the ‘Energy Human Resources Development Program’ of the Ministry of Trade, Industry and Energy and the Korea Energy Technology Evaluation Institute. Additional studies are underway through Thermology, a startup jointly founded by Professor Kim Su-hwan and Dr. Lee Jun, CEO of DOD Dermatology, to commercialize the findings into practical atopic dermatitis treatments.
According to the research team, atopic dermatitis is a refractory skin disease with one million patients (based on the 2022 National Health Insurance Service data) and is increasing by 2% annually. It occurs due to a complex interplay of factors including abnormalities in the skin barrier function, which acts as a protective layer, immune system dysfunction, and environmental factors, and no definitive treatment has yet been developed.
In this study, the team synthesized carbon dots using ‘polyphenols,’ extracted from green tea, and applied them to an atopic dermatitis model, demonstrating effects that improve the immune system and restore the skin barrier.
Professor Kim Su-hwan of Dong-A University’s Department of Chemical Engineering stated, “Based on this research, we plan to conduct focused studies to verify the efficacy of polyphenol-derived carbon dots in diseases related to immune system improvement.”
Research team from Dong-A University selected for publication and cover paper in 'ACS Applied Materials Interfaces' (from left: Professor Kim Suhwan, Professor Koo Minsu, Master Han Jungmin).
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